| Date | Location | Result | |
| 03/02/17 | Alumni Hall, Annapolis, Md. | Navy 49, Holy Cross 42 | Box score |
| 02/25/17 | Hart Center, Worcester, Mass. | Boston University 71, Holy Cross 68 (OT) | Box score |
| 02/22/17 | Hart Center, Worcester, Mass. | Holy Cross 63, Loyola (Md.) 62 | Box score |
| 02/19/17 | Bender Arena, Washington, D.C. | Holy Cross 69, American 54 | Box score |
| 02/15/17 | Hart Center, Worcester, Mass. | Army West Point 52, Holy Cross 47 | Box score |
| 02/12/17 | Hart Center, Worcester, Mass. | Holy Cross 61, Lehigh 45 | Box score |
| 02/08/17 | Kirby Sports Center, Easton, Pa. | Lafayette 69, Holy Cross 59 | Box score |
| 02/06/17 | Sojka Pavilion, Lewisburg, Pa. | Bucknell 82, Holy Cross 68 | Box score |
| 02/01/17 | Hart Center, Worcester, Mass. | Holy Cross 56, Colgate 50 | Box score |
| 01/28/17 | Alumni Hall, Annapolis, Md. | Navy 60, Holy Cross 47 | Box score |
| 01/25/17 | Reitz Arena, Baltimore, Md. | Loyola (Md.) 65, Holy Cross 62 | Box score |
| 01/23/17 | Hart Center, Worcester, Mass. | Holy Cross 63, American 55 | Box score |
| 01/18/17 | Christl Arena, West Point, N.Y. | Holy Cross 85, Army West Point 76 | Box score |
| 01/14/17 | Stabler Arena, Bethlehem, Pa. | Lehigh 68, Holy Cross 51 | Box score |
| 01/11/17 | Hart Center, Worcester, Mass. | Holy Cross 71, Lafayette 54 | Box score |
| 01/08/17 | Hart Center, Worcester, Mass. | Bucknell 68, Holy Cross 49 | Box score |
| 01/05/17 | Cotterell Court, Hamilton, N.Y. | Holy Cross 67, Colgate 61 | Box score |
| 01/02/17 | Hart Center, Worcester, Mass. | Holy Cross 51, Navy 50 | Box score |
| 12/30/16 | Case Gymnasium, Boston, Mass. | Boston University 61, Holy Cross 55 | Box score |
| 12/23/16 | Hart Center, Worcester, Mass. | Holy Cross 68, Marist 59 | Box score |
| 12/21/16 | William H. Pitt Center, Fairfield, Conn. | Holy Cross 72, Sacred Heart 67 | Box score |
| 12/18/16 | Thomas M. Ryan Center, Kingston, R.I. | Rhode Island 65, Holy Cross 54 | Box score |
| 12/11/16 | Hart Center, Worcester, Mass. | Holy Cross 75, Quinnipiac 57 | Box score |
| 12/07/16 | Cross Insurance Center, Bangor, Maine | Maine 55, Holy Cross 53 | Box score |
| 12/03/16 | Lundholm Gymnasium, Durham, N.H. | New Hampshire 56, Holy Cross 53 | Box score |
| 11/30/16 | SEFCU Arena, Albany, N.Y. | Holy Cross 55, Albany 49 | Box score |
| 11/27/16 | Hart Center, Worcester, Mass. | Monmouth 80, Holy Cross 77 | Box score |
| 11/25/16 | Hart Center, Worcester, Mass. | Holy Cross 73, South Carolina State 57 | Box score |
| 11/22/16 | Lavietes Pavilion, Cambridge, Mass. | Holy Cross 63, Harvard 52 | Box score |
| 11/20/16 | DCU Center, Worcester, Mass. | Massachusetts 68, Holy Cross 60 | Box score |
| 11/15/16 | Carrier Dome, Syracuse, N.Y. | Syracuse 90, Holy Cross 46 | Box score |
| 11/13/16 | Colonial Life Arena, Columbia, S.C. | South Carolina 81, Holy Cross 49 | Box score |